匡正
匡正，博士后，2021年博士毕业于北京大学前沿交叉学科研究院整合生命科学专业，目前在北京市农林科学院生物技术研究所从事植物miRNA的注释和演化历史的相关研究。主持国自然青年项目1项，参与国自然面上项目1项。已发表SCI论文9篇，其中第一或共同第一作者5篇，另有已第一作者身份向英文生物学系列图书Methods in Molecular Biology供稿1篇。
研究方向
基于基因组、sRNA-seq、机器学习等的植物miRNA注释、miRNA及其靶基因的演化历史解析等。
科研成果
承担的研究项目
| [1] | 国家自然科学基金委员会青年科学基金项目（主持）：“基于机器学习和三维结构的植物miRNA特征研究”（2023.1-2025.12） |
| [2] | 国家自然科学基金委员会面上项目（参与）：“植物microRNA注释新标准及microRNA靶基因对的选择机制研究”（2021.1-2024.12） |
主要研究成果
| [1] | Kuang, Z., Zhao, Y., Yang, X.# (2023). Plant MicroRNA Identification and Annotation Using Deep Sequencing Data. Part of the Methods in molecular biology book series (Clifton, N.J.) , 2595, 239–250. |
| [2] | Guo, Z., Li, B., Du, J., Shen, F., Zhao, Y., Deng, Y., Kuang, Z., Tao, Y., Wan, M., Lu, X., Wang, D., Wang, Y., Han, Y., Wei, J., Li, L., Guo, X.#, Zhao, C.#, Yang, X.# (2023). LettuceGDB: The community database for lettuce genetics and omics. Plant communications, 4(1), 100425. |
| [3] | Guo, Z., Kuang, Z., Zhao, Y., Deng, Y., He, H., Wan, M., Tao, Y., Wang, D., Wei, J., Li, L.#, Yang, X.# PmiREN2.0: from data annotation to functional exploration of plant microRNAs. Nucleic Acids Research (2022); 50(D1), D1475–D1482. |
| [4] | Guo, Z., Kuang, Z., Tao, Y., Wang, H., Wan, M., Hao, C., Shen, F., Yang, X.#, Li, L.# (2022). Miniature Inverted-repeat Transposable Elements Drive Rapid MicroRNA Diversification in Angiosperms. Molecular biology and evolution, 39(11), msac224. |
| [5] | Deng, Y., Zhang, H., Wang, H., Xing, G., Lei, B., Kuang, Z., Zhao, Y., Li, C., Dai, S., Yang, X.#, Wei, J.#, Zhang, J.# (2022). The Construction and Exploration of a Comprehensive MicroRNA Centered Regulatory Network in Foxtail Millet (Setaria italica L.). Frontiers in plant science, 13, 848474. |
| [6] | Zhao, Y., Kuang, Z., Wang, Y., Li, L.#, Yang, X.# (2021). MicroRNA annotation in plants: current status and challenges. Briefings in Bioinformatics, bbab075. |
| [7] | Deng, Y., Qin, Y., Yang, P., Du, J., Kuang, Z., Zhao, Y., Wang, Y., Li, D., Wei, J., Guo, X., Li, L.#, Yang, X.# (2021). Comprehensive Annotation and Functional Exploration of MicroRNAs in Lettuce. Frontiers in plant science, 12, 781836. |
| [8] | Guo, Z., Kuang, Z., Wang, Y., Zhao, Y., Tao, Y., Cheng, C., Yang, J., Lu, X., Hao, C., Wang, T., Cao, X., Wei, J., Li, L.#, Yang, X.# (2020).PmiREN: a comprehensive encyclopedia of plant miRNAs. Nucleic Acids Research 48, D1114–D1121. |
| [9] | Wang, Y., Kuang, Z., Li, L.#, Yang, X.# (2020). A Bioinformatics Pipeline to Accurately and Efficiently Analyze the MicroRNA Transcriptomes in Plants. Journal of visualized experiments: JoVE, (155), 10.3791/59864. |
| [10] | Kuang, Z., Wang, Y., Li, L.#, Yang, X.#, (2019). miRDeep-P2: accurate and fast analysis of the microRNA transcriptome in plants. Bioinformatics 35, 2521–2522. |
